{"id":3745,"date":"2026-08-07T11:03:55","date_gmt":"2026-08-07T11:03:55","guid":{"rendered":"https:\/\/mobileandwebsitedevelopment.com\/seam.ie\/?p=3745"},"modified":"2026-08-07T11:04:09","modified_gmt":"2026-08-07T11:04:09","slug":"innovation-partnership-unveiling-the-future-of-dry-powder-inhalers-through-advanced-simulation-and-high-speed-x-ray-imaging","status":"publish","type":"post","link":"https:\/\/mobileandwebsitedevelopment.com\/seam.ie\/innovation-partnership-unveiling-the-future-of-dry-powder-inhalers-through-advanced-simulation-and-high-speed-x-ray-imaging\/","title":{"rendered":"Innovation Partnership &#8211; Unveiling the Future of Dry Powder Inhalers through Advanced Simulation and High-Speed X-Ray Imaging"},"content":{"rendered":"<p><strong>Project Title: Development of Capsule Type Respiratory Products<\/strong><\/p>\n<p><strong>Client Name: Teva Pharmaceuticals<\/strong><\/p>\n<p><strong>Unveiling the Future of Dry Powder Inhalers through Advanced Simulation and High-Speed X-Ray Imaging<\/strong><\/p>\n<h4><strong>Introduction:<\/strong><\/h4>\n<p>Teva, a global leader in generic and speciality medicines, has made groundbreaking strides in the development of its new line of capsule dry powder inhalers. Leveraging state-of-the-art technologies like Computational Fluid Dynamics (CFD) and High-Speed X-ray imaging, this project offers unparalleled insights into inhaler performance, laying the groundwork for superior inhaler designs that promise improved patient outcomes.<\/p>\n<h4><strong>The Challenge:<\/strong><\/h4>\n<p>Previous research for Teva devices faced a daunting roadblock: the inability to validate CFD models of particle flows with real-time imaging. Traditional optical techniques fell short in capturing the intricate internal dynamics of the inhaler, highlighting the need for innovative solutions.<\/p>\n<h4><strong>Our Approach: A Comprehensive Investigation<\/strong><\/h4>\n<p>The research project was structured into five critical tasks:<\/p>\n<p><strong>XMT and CFD Inhaler Modelling<\/strong>: We developed a reliable CT CFD model of the inhaler, utilising software tools such as VGStudio Max, MeshLab, and SpaceClaim.<\/p>\n<p><strong>CFD Modelling of Capsule Movement<\/strong>: Advanced simulations were conducted to explore the capsule&#8217;s influence on pressure drop distribution and angular velocity.<\/p>\n<p><strong>Analysis of Capsule Dose Evacuation<\/strong>: Particle motion methodologies were incorporated to accurately predict capsule evacuation.<\/p>\n<p><strong>High-Speed X-Ray Imaging<\/strong>: Employing custom-developed imaging techniques, we achieved real-time visualisation of the inhaler&#8217;s internal mechanisms.<\/p>\n<p>Custom Particle Model: Utilising ANSYS Fluent UDF for particle force history monitoring, we gained insights into particle dynamics, including wall collisions and turbulence effects.<\/p>\n<h4><strong>Results and Validation:<\/strong><\/h4>\n<p>High-speed X-ray imaging allowed us to validate our CFD models effectively. The strong correlation between simulation and real-world observation underscored the model&#8217;s accuracy in predicting realistic capsule and particle motion. This successful validation marks a significant milestone in the understanding of the clinical performance of dry powder inhalers.<\/p>\n<p>&nbsp;<\/p>\n<p><img fetchpriority=\"high\" decoding=\"async\" class=\"alignnone wp-image-2239\" src=\"https:\/\/seam.ie\/wp-content\/uploads\/TEV-2-300x180.png\" alt=\"\" width=\"337\" height=\"202\" \/>\u00a0 \u00a0 \u00a0 \u00a0 <img decoding=\"async\" class=\"alignnone size-medium wp-image-2237\" src=\"https:\/\/seam.ie\/wp-content\/uploads\/Tev-4--300x208.jpg\" alt=\"\" width=\"300\" height=\"208\" \/><\/p>\n<p>&nbsp;<\/p>\n<p><strong>Impact and Future Prospects:<\/strong><\/p>\n<p>The methodologies and findings from this project not only deepen our understanding of inhaler dynamics but also serve as a stepping stone for future research. By achieving these innovative results, Teva stands poised to lead the industry in the development of more effective inhaler designs, thus improving patient outcomes.<\/p>\n<p><strong>Mr Dan Buck<\/strong> Senior Director at TEVA said <em>\u201cTeva have had a close working\u00a0 relationship with SEAM for over 15 years and this project is another example of what can be achieved with a collaborative mind-set\u201d<\/em><\/p>\n<p><em>\u00a0<\/em><strong>Dr Ramesh Raghavendra<\/strong><em> Centre Director at SEAM said \u201cWe take pride in collaborating with Irish based industries and this innovation partnership project with Teva is a great \u00a0example of what happens when you establish strong relationship and get talented people across the aisles meet together with marketing leading technology that is on offer \u201d<\/em><\/p>\n<p>If you would like to learn more about the innovation partnership Programme please click here or contact us at SEAM to discuss the benefits of an innovation partnership.<\/p>\n<p>Download PDF Version Here\u00a0<strong>innovation partnership TEVA &amp; SEAM (4)<\/strong><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Project Title: Development of Capsule Type Respiratory Products Client Name: Teva Pharmaceuticals Unveiling the Future of Dry Powder Inhalers through<\/p>\n","protected":false},"author":1,"featured_media":3747,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[18],"tags":[],"class_list":["post-3745","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"acf":[],"_links":{"self":[{"href":"https:\/\/mobileandwebsitedevelopment.com\/seam.ie\/wp-json\/wp\/v2\/posts\/3745","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mobileandwebsitedevelopment.com\/seam.ie\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mobileandwebsitedevelopment.com\/seam.ie\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mobileandwebsitedevelopment.com\/seam.ie\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/mobileandwebsitedevelopment.com\/seam.ie\/wp-json\/wp\/v2\/comments?post=3745"}],"version-history":[{"count":1,"href":"https:\/\/mobileandwebsitedevelopment.com\/seam.ie\/wp-json\/wp\/v2\/posts\/3745\/revisions"}],"predecessor-version":[{"id":3746,"href":"https:\/\/mobileandwebsitedevelopment.com\/seam.ie\/wp-json\/wp\/v2\/posts\/3745\/revisions\/3746"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mobileandwebsitedevelopment.com\/seam.ie\/wp-json\/wp\/v2\/media\/3747"}],"wp:attachment":[{"href":"https:\/\/mobileandwebsitedevelopment.com\/seam.ie\/wp-json\/wp\/v2\/media?parent=3745"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mobileandwebsitedevelopment.com\/seam.ie\/wp-json\/wp\/v2\/categories?post=3745"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mobileandwebsitedevelopment.com\/seam.ie\/wp-json\/wp\/v2\/tags?post=3745"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}